KTH Royal Institute of Technology, Stockholm, Sweden
KTH Summer school Computational Tissue Biomechanics Making sense of data
- Ages
- 18+
- Duration
- 3 + 5 days
- When
- 2027 dates pending
Summary
Introduces and applies state-of-the-art tools in the continuum mechanical analysis of biological tissues.
Introduction and Motivation. As biomechanical properties of tissues are tightly linked to pathologies, the description of mechanical tissue properties is instrumental to advance our understanding of disease development and progression.
Pathology often manifests through the alteration of tissue mechanical properties long before clinical imaging modalities are able to see any structural or functional changes.
Formed by cells embedded in the Extra Cellular Matrix (ECM), biological tissue exhibits intricate microstructural characteristics, factors that then govern its micro-mechanical and macro-mechanical properties.
The analysis of how load (stress and strain) transmits across said scales and therefore stimulates cell function, is challenging and requires trustworthy biomechanical models.
A plethora of mechanical testing has been reported, and, as no testing standards for biological tissue exist - individual laboratories implement individual protocols. A similar observation characterizes the design of biomechanical computational models.
Besides hindering the cross-comparison, low-quality experimental data as well as poor biomechanical models challenge the exploration of biological phenomena. In conclusion, the biomechanical community requires an educational program to develop a solid foundation in the analysis of biological tissues.
It is the proper integration of experimental tissue characterization and computational biomechanical analysis that guarantees progress in the field.
Camp highlights
- The course introduces and applies state-of-the-art tools in the continuum mechanical analysis of hard and soft biological tissues
- Regardless of numerous scientific meetings that report the latest research results, they fail to communicate the basics of tissue biomechanics
- This course therefore provides attendees with a broad foundation towards the mechanical description of biological tissues, allowing to address individual scientific endeavors more effectively
- The course is designed for PhD students and postdoctoral researchers with a good background in bioengineering and solid mechanics
- It integrates physical principles, numerical approaches, and experimental concepts towards the characterization of biological tissues. The program’s holistic approach is unique in the analysis of biological tissues
Dates and prices
2027 dates pending
3 + 5 days
2027 prices pending
The camp confirms availability when you enquire.
What the price covers
Full inclusion details
- Lectures
- Hands-on laboratory
- Ask the expert sessions
- State-of-the-art tools
- Social Program
Programme and activities
What you’ll do
- Art
Module I: Basics Wednesday, Aug. 12th 8.00-9.00: Registration to Modul I 9.00-12.00 Continuum mechanics 12.00-14.00 Lunch break 14.00-17.00 Continuum mechanics
Thursday, Aug. 13th 9.00-12.00 Finite element method 12.00-14.00 Lunch break 14.00-17.00 Finite element method
Friday, Aug. 14th 9.00-12.00 Constitutive modeling 12.00-14.00 Lunch break 14.00-17.00 Constitutive modeling
Module II: Applications Monday, Aug. 17th 8.15-10.15 Non-linear Continuum Biomechanics 10.15-10.45 Coffee break 10.45-12.45 Constitutive modeling 12.45-14.00 Lunch break 14.00-15.15 Ask the expert 15.30-18.00 In-vitro tissue testing (group 1) 15.30-18.00 FEM modelling (group 2)
Tuesday, Aug. 18th 8.15-10.15 Data Analysis 10.15-10.45 Coffee break 10.45-12.45 Vascular tissue 12.45-14.00 Lunch break 14.00-15.15 Ask the expert 15.30-18.00 In-vitro tissue testing (group 2) 15.30-18.00 FEM modelling (group 3)
Wednesday, Aug. 19th 8.15-10.15 Bone 10.15-10.45 Coffee break 10.45-12.45 Tendon, Ligament, Cartilage 12.45-14.00 Lunch break 14.00-15.15 Ask the expert 15.30-18.00 In-vitro tissue testing (group 3) 15.30-18.00 FEM modelling (group 4)
Thursday, Aug. 20th 8.15-10.15 The basics of non-invasive clinical imaging modalities 10.15-10.45 Coffee break 10.45-12.45 ex-vivo tomography 12.45-14.00 Lunch break 14.00-15.15 Ask the expert 15.30-18.00 In-vitro tissue testing (group 4) 15.30-18.00 FEM modelling (group 1)
Friday, Aug. 21st 8.15-10.15 Brain/head 10.15-10.45 Coffee break 10.45-11.15 Ask the expert 11.15-13.30 Lunch break 13.30-15.00 Multiple choice test in groups of four students
Social activities Sunday, Aug.16th 17.30-18.30 Boat tour through The Royal National City Park and registration to Module II
Monday, Aug. 17th 16.00-17.00 Guided tour around KTH campus (group 3)
Tuesday, Aug. 18th 16.00-17.00 Guided tour in Nobel Prize Museum (group 1)
Wednesday, Aug. 19th 16.00-17.00 Guided tour around KTH campus (group 1,2)
Thursday, Aug. 20th 16.00-17.00 Guided tour in Nobel Prize Museum (group 2,3) 19.30-22.15 Dinner
Friday, Aug. 21st 20.00- Pub night
Academics
- Artem Kulachenko, KTH Royal Institute of Technology, Sweden
- David Marlevi, Karolinska Institute, Sweden
- Gerard A. Ateshian, Columbia University, US
- Hanna Isaksson, Lund University, Sweden
- Marco Viceconti, University of Bologna, Italy
- Svein Kleiven, KTH Royal Institute of Technology, Sweden
- T. Christian Gasser, KTH Royal Institute of Technology, Sweden
- Vikram S. Deshpande, Cambridge University, UK
- Continuum biomechanics and FEM (Gasser)
- Conservation laws (Deshpande)
- Constitutive modelling (Ateshian)
- Data exploration (Kulachenko)
- Clinical imaging modalities (Marlevi)
- Bone tissue (Viceconti)
- Ligament/tendon/articular cartilage (Isaksson)
- Cardiovascular tissue (Gasser)
- Brain (Kleiven)
Accommodation and meals
Location and travel
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